February 25, 2014
The European Food Safety Authority (EFSA) under the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) is inviting the public for consultation the draft opinion on the potential risks of bisphenol A (BPA).
The draft opinion includes the re-evaluation of the tolerable daily intake (TDI) for BPA by lowering the TDI by ten-fold, from its current level of 50μg/kg of body weight/day to 5μg/kg of body weight/day. EFSA has reviewed 450 studies relating to BPA then concludes that the exposure to the substance will likely to adversely affect the kidney and liver.
EFSA-CEF has based their evaluation based on three steps:
- weight-of-evidence approach for health hazards that previous scientific studies and reviews suggest are associated with BPA exposure;
- statistical method known as the benchmark dose approach to estimate the level at which BPA causes a small but measurable effect on the kidney, liver and mammary gland in animals; and
- assessment of new research results into the way BPA behaves in the bodies of animals compared to humans.
The public consultation is open until March 13, 2014.