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EPCS Certification List

Please see below for a list of products that have successfully completed the formal EPCS testing and certification process.

Overview

The Drug Enforcement Administration (DEA) mandates that applications used for prescribing or filling Electronic Prescriptions for Controlled Substances meet all the requirements stated in 21 CFR Part 1311 Subpart C. The following EPCS Certified Applications Lists identify products that have successfully completed the formal EPCS testing and certification process through UL’s laboratory in California (formerly known as Infogard Laboratories Inc.).

Products are certified for a time period of two years from the date of certificate issuance. Use of an EPCS certified application is the first step to legally fill or prescribe controlled substances electronically. Pharmacies and prescribers must also complete an audit process to address processing integrity (prevention of insider threats and outsider attacks). UL provides a DEA approved process for verifying processing integrity.

The following EPCS Certified Applications Lists identify products that have successfully completed the formal EPCS testing and certification process.

Pharmacy EPCS Certified Applications 

Certification # Company Name Product Name Product Version # Pharmacy Application  Expiration Date
4791025180C1 RNA Holdings LLC d/b/a CareSmart LLC Helix GPS Pharmacy Management System 1.12.79 Pharmacy Application 10/27/2025
4788988653C5 U.S. Department of Veterans Affairs Computerized Patient Record System (CPRS) and Veterans Health Information Systems and Technology Architecture (VistA) CPRS GUI Version 32.221 (OR*3*598) Pharmacy Application 9/2/2025
4790781163C1 PCCA RxDispense 2.3.8 Pharmacy Application 7/7/2025
4790839221C1 Keycentrix Newleaf 2 Pharmacy Application 7/16/2025
4790701794C1 AdvanceNet Health Solutions Inc. ePostRx [1] with eRxScribe [2] 2023 Build 001 [1] with 2023 Build 001 [2] Pharmacy Application 4/30/2025
4790507036C1 DAA Enterprises Inc. Visual SuperScript A.930A Pharmacy Application  8/15/2024
4790524727C1 Foundation Systems, Inc. FSI Pharmacy Management System 22.08 Pharmacy Application  8/28/2024
4790462835C1 Framework MI Inc. Cleo Suite 2.5.27.49 Pharmacy Application  5/25/2025
4790442127C1 Genoa Technology, Inc. PROscript 2000 5.4 Pharmacy Application  7/22/2024
4790712976C1 LexiCom Computer Systems, LLC ProScript Pharmacy Software 40.8(100) Pharmacy Application 3/26/2025
4790312259C1 PK Software The Compounder 6.1.1.4 Pharmacy Application  5/4/2024
4790362030C1 Software Strategies Inc. RxMaster Pharmacy System 17.4 Pharmacy Application  6/24/2024
4790280646C1 VIP Computer Systems, Inc. VIP E-Prescription System 6.5.4 Pharmacy Application  2/28/2024

Prescriber EPCS Certified Applications

Certification # Company Name Product Name Product Version # Prescription Application  Expiration Date
4790967085C1 GeniusDoc Inc. GeniusDoc 12.0 Prescription Application 10/15/2025
4788988653C6 U.S. Department of Veterans Affairs Computerized Patient Record System (CPRS) and Veterans Health Information Systems and Technology Architecture (VistA) CPRS GUI Version 32.221 (OR*3*598) Prescription Application  9/2/2025
4789834939C1 CompuGroup Medical Aprima EPCS 1.1 Prescription Application  4/29/2024
4790593239C1 Athenahealth, Inc athenaClinicals and athenaOne Mobile 22.11 Prescription Application 3/16/2025
4790196736C1 Auto Medical, LLC Med-A-Morphosis 3 Prescription Application 12/21/2024
4790625380C1 Enabledoc LLC enablemypractice EHR 5 Prescription Application 12/7/2024
4790362870C1 Family Health Centers of San Diego CMIS Medical EHR 2.0 Prescription Application  6/5/2024
4790531714C1 Goldblatt Systems LLC Clinical Semantic Network (CSN) 8 Prescription Application  10/28/2024
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