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US EPA Releases Update to TSCA Chemical Substance Inventory

The TSCA Chemical Substance Inventory includes more than 86,000 substances that are or once were in commerce in the United States. The Inventory was updated in Feb. 2023.

Equipment and glassware for test product extraction and orange color solution

February 27, 2023

By John Kowalski, senior regulatory specialist, Supply Chain Team, UL Solutions, with contributions from Chelsea Lane

On Feb. 16, 2023, the U.S. Environmental Protection Agency (EPA) released an update to the non-confidential version of the Toxic Substances Control Act (TSCA) Chemical Substance Inventory.  This was the first update to the non-confidential Inventory since February 2022.

The TSCA Inventory is, in essence, a list of chemical substances that are or once were in commerce in the United States.  The latest update to the Inventory includes more than 86,000 substances.

Substances listed on the Inventory are designated as active or inactive in U.S. commerce.  Approximately 49 percent of the substances listed on the latest update are designated as active.

Under TSCA Section 5, companies must notify EPA at least 90 days before manufacturing or importing a chemical substance that is not listed on the Inventory for a non-exempt, commercial purpose subject to regulation under TSCA.  They must do so by preparing and electronically submitting a premanufacture notice (PMN).

Under TSCA Section 8, companies must notify EPA before manufacturing, importing, or processing a chemical substance that is designated as inactive on the Inventory, but not more than 90 days before.  They must do so by preparing and electronically submitting a Notice of Activity (NOA) Form B.

Our ChemADVISOR® Regulatory Database has already been updated against the updated TSCA Inventory.  In addition, our subject matter experts can assist companies with the preparation and submission of PMNs and NOA Form Bs.

EPA TSCA Chemical Substance Inventory Web Page

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