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Chilean List of Chemical Substances Updated

Chile's revised Official GHS Substance Classification List, published on 21 August 2026, aligns with recent EU CLP updates and introduces new hazard classifications that may impact SDSs and labeling obligations for chemical products.

Gloved hands pipetting yellow liquid into flask

November 13, 2026

By Raissa Havens, Senior Regulatory Specialist, Software, UL Solutions

The Chilean Ministry of Health published an updated version of the Official List of Classified Substances, significantly expanding and revising the country's GHS hazard classification database. The update was issued on 21 August 2026 as part of Chile's implementation of Supreme Decree No. 57 of 2021.

The Official List was originally published on 23 August 2021, and is to be used as a minimum reference for manufacturers and importers in Chile to classify their products. Later, in April 2022, an amendment was published, correcting several entries and improving data accuracy.

The 2026 revision incorporates modifications from the European CLP Annex VI classification through 2026, including revised ATP references. Besides new substances added to the list, there have been revisions to hazard classifications, specific concentration limits, M-factors, and acute toxicity estimates (ATEs) values.

The updated list is available through the Chilean Ministry of Health's GHS portal and will become enforceable six months after publication.

As Chile continues its phased implementation of GHS, the final compliance deadline remains 9 February 2027 for mixtures intended for uses other than industrial applications.

UL’s ChemADVISOR™ Regulatory Database is being updated to reflect the changes and will be available for quarter 2027-1 (January 2027) release.

Chemical manufacturers, importers and downstream users, should review the updated list, as these changes can directly affect SDSs, labels, and overall compliance obligations in Chile.

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